In a new paper from the Strynadka lab, researchers show the structure of the EspA filament from enteropathogenic E.Coli. Enteropathogenic E.Coli used the a multi-protein assembly called the Type III Secretion System to deliver proteins to host cells. The EspA filament is an extension to the Type III secretion system required for bacterial colonization of the gut. This new structure gives insight into how proteins may be able to move through the filament into the host cell.
A new structure of the EspA filament provides insight into how proteins are secreted from enteropathogenic E.Coli.