Francia et al, A magnetic separation method for isolating and characterizing the biomolecular corona of lipid nanoparticles, PNAS, 2024
Li et al, Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance, Science Advances, 2024
Haji-Ghassemi et al, Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation, Science Advances, 2023
Harris et al, Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain, eLife, 2023
Cholak et al, Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives, Structure, 2023
Mo et al, Light-Activated siRNA Endosomal Release (LASER) by Porphyrin Lipid Nanoparticles, ACS Nano, 2023
Meulewaeter et al, Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures, Journal of Controlled Release, 2023
Chen et al, Induction of Bleb Structures in Lipid Nanoparticle Formulations of mRNA Leads to Improved Transfection Potency, Advanced Materials, 2023
Sexton et al, The cell envelope of Thermatogae suggests a mechanism for outer membrane biogenesis, PNAS, 2023
Weisser et al, An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity, Nature Communications, 2023
Alexander et al, Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus, Nature, 2023
Vasyliuk et al, Conformational landscape of the yeast SAGA complex as revealed by cryo-EM, Scientific Reports, 2022
Willegems et al, Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277, Nature Communications, 2022
Dalwadi et al, Biochemical and Structural Characterization of Human Core Elongator and Its Subassemblies, ACS Omega, 2022
Sexton et al, Super-resolution confocal cryo-CLEM with cryo-FIB milling for in situ imaging of Deinococcus radiodurans, Current research in Structural Biology, 2022
Sexton et al, Ultrastructure of organohalide-respiring Dehalococcoidia revealed by cryo-electron tomography, Applied and Environmental Microbiology, 2021
Fernandes Scortecci et al, Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease, Nature Communications, 2021
Rathinaswamy, Dalwadi et al, Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation, Science Advances, 2021
Harris et al, Biochemical Insight into Novel Rab-GEF Activity of the Mammalian TRAPPIII Complex, JMB, 2021
Woll et al, Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM, Nature Communications, 2021
Henrickson et al, Density Matching Multi-wavelength AnalyticalUltracentrifugation to Measure Drug Loading of Lipid Nanoparticle Formulations, ACS Nano, 2021
Lyons et al, Cryo-EM structure of the EspA filament from enteropathogenic Escherichia coli: revealing the mechanism of effector translocation in the T3SS, Structure, 2021
Hepburn et al, The active DNA-PK holoenzyme occupies a tensed state in a staggered synaptic complex, Structure, 2021
Sexton and Tocheva, Ultrastructure of Exospore Formation in Streptomyces Revealed by Cryo-Electron Tomography, Front. Microbiol., 2020
Ma et al, Structural basis for diamide modulation of ryanodine receptor, Nature Chemical Biology, 2020
Majewski et al, Cryo-EM analysis of the SctV cytosolic domain from the Enteropathogenic E.coli T3SS injectisome, J. Structural Biology, 2020
Hu et al, Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin, Nature Communications 9, 2018
Kulkarni et al, Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA, ACS Nano, 2018