Sophia Russo
Structure of Rab3GAP, guanine nucleotide exchange factor for Rab18 GTPase, obtained by Fairlie and Nguyen et al. (2025)
A new structure of the guanine nucleotide exchange factor, Rab3GAP, offers insight into its activation of Rab18 GTPase and many essential cellular functions. In a January 2025 publication in Nature Communications, Fairlie, Nguyen and colleagues discuss their high-resolution structure of the Rab3GAP catalytic core. One crucial observation lies in the elusive interaction of the two […]
Magnetic lipid nanoparticles were applied in exciting new technique by Francia, Zhang et al. (2024)
A clever new technique from the Cullis Lab is allowing researchers to better understand how our bodies interact with lipid nanoparticles (LNPs) by making them magnetic. LNPs are a powerful tool for the delivery of drugs and the application of gene therapies. As Francia, Zhang and colleagues explain in their 2024 PNAS publication, biomolecules […]
